Description
S100a4 belongs tothe S100 super-family of proteins containing 2 EF-hand calcium bindingdomains. This protein is ubiquitously overexpressed and is localized in thecytoplasm and/or nucleus. S100a4 may play a role in motility, invasion, andtubulin polymerization. Chromosomal rearrangements and altered expression ofthe S100a4 have been implicated in tumor metastasis